|
Symbol Name ID |
Dsg2
desmoglein 2 MGI:1196466 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating troponin I concentration |
Right ventricular cardiomyopathy |
Dilated cardiomyopathy |
Severely reduced left ventricular ejection fraction |
Increased left ventricular end-diastolic volume |
Prolonged PR interval |
Epsilon wave |
Sudden cardiac death |
Palpitations |
Ventricular tachycardia |
Ventricular arrhythmia |
Premature ventricular contraction |
Left bundle branch block |
Right bundle branch block |
Congestive heart failure |
| Disease(s) Associated with DSG2 | |||||||||||||||
| arrhythmogenic right ventricular dysplasia 10 | |||||||||||||||
| dilated cardiomyopathy 1BB |
| Mouse Phenotypes | cardiovascular system phenotype |
abnormal intercalated disk morphology |
abnormal cardiovascular development |
cardiac hypertrophy |
abnormal heart ventricle morphology |
abnormal heart left ventricle wall morphology |
dilated heart left ventricle |
abnormal heart right ventricle wall morphology |
hemopericardium |
cardiac fibrosis |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
abnormal heart echocardiography feature |
decreased left ventricle systolic pressure |
decreased right ventricle systolic pressure |
irregular heartbeat |
ventricular premature beat |
abnormal heart electrocardiography waveform feature |
decreased P wave amplitude |
abnormal QRS complex |
increased Q wave amplitude |
decreased QRS amplitude |
prolonged QRS complex duration |
abnormal S wave |
increased cardiomyocyte apoptosis |
cardiomyopathy |
heart inflammation |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||
| Dsg2em1Spin/Dsg2em1Spin | ||||||||||||||||||||||||||||
| Dsg2tm1a(EUCOMM)Wtsi/Dsg2tm1a(EUCOMM)Wtsi | ||||||||||||||||||||||||||||
| Dsg2tm1b(EUCOMM)Wtsi/Dsg2tm1b(EUCOMM)Wtsi | ||||||||||||||||||||||||||||
| Dsg2tm1d(EUCOMM)Wtsi/Dsg2tm1d(EUCOMM)Wtsi | ||||||||||||||||||||||||||||
| Dsg2em1Spin/Dsg2+ | ||||||||||||||||||||||||||||
| Dsg2tm1d(EUCOMM)Wtsi/Dsg2+ | * | |||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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